New Products; Therapeutics Focus: Fungal Infections

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Bioré Skincare Launches Limited Edition Deep Cleansing Pore Strips

Bioré Skincare introduced new Limited Edition Deep Cleansing Pore Strips, and celebrated the launch by partnering with Girl Up, a United Nations Foundation campaign.

Girl Up mobilizes girls and women across the globe to raise awareness and funds for United Nations programs that help adolescent girls in need. The charity’s SchoolCycle initiative provides bicycles to girls in developing countries so they can access education and stay in school.

With actress and Brand Ambassador Shay Mitchell supporting the partnership, Bioré® Skincare is donating 200 bikes.

Bioré Skincare Limited Edition Deep Cleansing Pore Strips are available for a limited time at select stores. biore.com

Colorescience Introduces All Calm Clinical Redness Corrector for Rosacea

Colorescience introduced All Calm Clinical Redness Corrector to help neutralize redness with its subtle green undertones. The patent-pending BioSolace complex helps provide ongoing relief from sensitivity and the appearance of redness. In addition, it includes full-spectrum UVA/UVB SPF 50 sun protection via 100 percent mineral, chemical-free active ingredients.

“It’s such a great feeling to see a smiling rosacea patient after they have tried All Calm for the first time. It addresses and covers redness, acts as a moisturizing color corrector, and sunscreen all in one,” says Dr. Shari Topper, a Board Certified Dermatologist in Boca Raton, FL and a key Colorescience® physician partner, in a news release.

All Calm is available through a network of dermatologists and licensed skincare professionals. Colorescience.com

Isdin Launches Nutraseb for Facial Seborrheic Dermatitis

Nutraseb Facial Cream, a new steroid-free topical prescription treatment for the multi-symptom management of facial seborrhea and seborrheic dermatitis (SD), is now available from Isdin. Nutraseb is a fragrance free, water-based emulsion formulated to target all four aspects of SD: inflammation, fungus, sebum, and scaling.

In one study that evaluated the efficacy of Nutraseb for mild facial seborrheic dermatitis, the cream was successful in 87.5 percent of patients with mild dermatitis, and 78.8 percent of patients considered the cream to be good or excellent. A significant number of patients had a decrease in erythema as well. A second study demonstrated that after 20 people used the treatment for 21 days, more than 90 percent reported improvement of their symptoms, with the added bonus of skin moisturization. Isdin.com

Revision Skincare Expands Line with Nectifirm Advanced

Revision Skincare is expanding the Nectifirm collection with Nectifirm Advanced. Nectifirm Advanced harnesses the power of the microbiome for maintaining skin health. Active ingredients such as Diglucosyl Gallic Acid work with the skin’s own microbiome to enhance natural mechanisms for brighter, more even skin tone. Nectifirm Advanced also contains a proprietary blend of eight distinctive peptides to lessen the look of fine lines and wrinkles. Lingonberry Extract helps the skin enhance its own antioxidant system while an extract of Red Microalgae soothes and provides a lifting effect. Multiple other specialized ingredients slim and form the neck by addressing adipose tissue, the company states.

Nectifirm Advanced is available exclusively through dermatologists, plastic surgeons, and medical spas. Revisionskincare.com


Therapeutic Focus: Fungal Infections

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After the Diagnosis: Managing Patients with Onychomycosis
Once the diagnosis of onychomycosis is confirmed, Molly Hinshaw, MD says the next step is educating patients for optimal results with medical management of this nail disorder. She offers tips for improving compliance for best treatment outcomes and happy patients.

Research: Nitric Oxide-Releasing Nanoparticles For Skin InfectionS

George Washington University (GW) researchers have found that topically applied nitric oxide-releasing nanoparticles (NO-np) are a viable treatment for deep fungal infections of the skin caused by dermatophytes.

While superficial infections can often be managed with topical agents, fungal infections which infiltrate the hair follicle or into deeper layers of the skin can only be effectively treated with oral or systemic antifungal therapies. Topical antifungals offer limited penetration through the skin.

Adam Friedman, MD, associate professor of dermatology at the GW School of Medicine and Health Sciences and collaborators at the Albert Einstein College of Medicine turned to NO.

In an animal model, the research team found that NO-np facilitated a quicker, more impactful response to treatment over the commercially available topical terbinafine, showing 95 percent of infection clearance by the third day of treatment.

“The next step is to scale up the technology for clinical trial use in several therapeutic areas given the diverse clinical implications of the nitric oxide producing nanoformulation, as well as the platform overall given its unique ability to encapsulate and deliver a broad range of active ingredients,” Dr. Friedman explained.

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