Recent in vitro and animal testing data from Novan Therapeutics indicate that the company's drug candidate, SB204, could lead to a topical treatment for acne that reduces oil production in the skin. Dr. Diane Thiboutot, Professor of Dermatology at Penn State Hershey College of Medicine, notes that, “Inhibiting the production of sebum is critical to affecting the acne disease process. Orally administered therapies that can reduce oily secretions of the skin have traditionally shown good clinical responses. At this time, I am not aware of any topically applied therapy that can reduce sebum production.”