Aclaris Announces Pricing of Initial Public Offering

Aclaris Therapeutics, Inc. announced the pricing of its initial public offering of 5,000,000 shares of its common stock at a price to the public of $11.00 per share. The shares, approved for listing on The NASDAQ Global Select Market, will be traded under the ticker symbol ACRS. All of the common stock is being offered by Aclaris. In addition, Aclaris has granted the underwriters a 30-day option to purchase up to 750,000 additional shares of common stock at the initial public offering price. The offering is expected to close on October 13, 2015, subject to customary closing conditions.

Jefferies LLC and Citigroup Global Markets Inc. are acting as joint book-running managers for the offering. William Blair & Company, L.L.C. is acting as a co-manager.

The offering will be made only by means of a prospectus. A copy of the final prospectus, when available, may be obtained from Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, 2nd Floor, New York, NY 10022, by telephone at (877) 547-6340 or by email at prospectus_department@jefferies.com, or Citigroup Global Markets Inc., c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, New York 11717, by telephone at (800) 831-9146, or by email at prospectus@citi.com.

A registration statement relating to these securities was declared effective by the Securities and Exchange Commission on October 6, 2015.