Research Brief: Personalized Bacteriotherapy May Improve Skin Microbiome and Symptoms in AD


Bacteriotherapy with an autologous strain of bacteria may safely improve S. aureus colonization in the microbiome of patients with atopic dermatitis (AD) and improve disease severity, a new study suggests.

In this clinical trial of 11 patients with eczema, researchers saw a 99.2 percent reduction in staphylococcus aureus colonization and observed significant clinical improvement as well.

“Although larger studies will be needed, this personalized approach for S aureus reduction may provide an alternative treatment for patients with AD beyond antibiotics, immunosuppression, and immunomodulation, “ conclude researchers from the University of California San Diego School of Medicine.

The study appears in JAMA Dermatology.

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