Researchers Analyze Social Media Posts on JAK Inhibitors

An analysis of social media posts concluded that patients are most concerned about the efficacy and side effects of JAK inhibitors and issues regarding access to them, according to a new Archive of Dermatological Research article by members of the University of Nebraska Medical Center’s Department of Dermatology.

“Our objective is to better understand patient concerns, reported side effects, and sentiments regarding the use of JAK inhibitors for dermatologic disease,” the authors wrote in “Analysis of patient experiences regarding JAK inhibitors for atopic dermatitis, psoriasis, alopecia areata, and vitiligo.”

A cross-sectional analysis was performed on the most frequented subreddits for dermatologic disease in which JAK inhibitors have obtained FDA approval (r/atopic dermatitis, r/psoriasis, r/alopecia areata, r/vitiligo, and r/eczeJAKS). The sentiment, central theme, and engagement level of each post was evaluated using previously utilized methods. Efficacy was a focus in 47% of the 923 posts analyzed, and medication-related side effects were a focus in 16%. Other areas of interest included payment/insurance (9%), study results/news (7%), administration/dosage (4%), and medication interactions (3%). Reported side effects also were analyzed.

“Providers can use the insights gained from this study to address hesitancy better and guide comprehensive, patient-centered discussions with patients regarding JAK inhibitor use,” the authors wrote.