Showing 181-190 of 381 results for "".
- Analysis: Fibrosis Mechanisms in Systemic Sclerosis Skinhttps://practicaldermatology.com/news/fibrosis-mechanisms-ssc-skin/2470860/Researchers have identified a shift toward reticular gene expression in systemic sclerosis (SSc) skin, with disruptions in WNT/β-catenin signaling playing a key role in these changes. Authors for the study, published in Arthritis and Rheumatology, analyzed skin morphology and mole
- Method Review: A Closer Look at Cryo-EM’s Impact on Dermatologyhttps://practicaldermatology.com/news/method-review-a-closer-look-at-cryo-ems-impact-on-dermatology/2470806/A recent method review in the Journal of Investigative Dermatology points to the potential of cryogenic electron microscopy (cryo-EM) in dermatological research. According to the authors, advanced imaging technology enables atomic-resolution visualization of macromolecules in thei
- Key Thickness Benchmark Identified for Thin Melanoma Death Riskhttps://practicaldermatology.com/news/key-thickness-benchmark-identified-thin-melanoma-death-risk/2470668/Melanomas with Breslow thickness between 0.8 and 1.0 mm are associated with nearly triple the risk of melanoma-related death compared to thinner melanomas, a new study of Australian registry data reports. "Most patients who present with primary cutaneous melanomas have thin tumors (≤ 1.0 m
- Study: Cutaneous Lupus Linked With Elevated Cardiovascular Disease Riskhttps://practicaldermatology.com/news/study-cutaneous-lupus-linked-elevated-cardiovascular-disease-risk/2468723/Patients with cutaneous lupus erythematosus (CLE) face an elevated risk of atherosclerotic cardiovascular disease (ASCVD), comparable to that seen in systemic lupus erythematosus (SLE), according to a new study. Authors of the retrospective cohort study analyzed health records of 8,138 pat
- Analysis: Higher Infection and Acne Risks with JAK Inhibitors in ADhttps://practicaldermatology.com/news/analysis-higher-infection-and-acne-risks-jak-inhibitors-ad/2468381/Researchers for a new analysis have provided a data and analytics framework for the evaluation of the safety of immune-modulating drugs (IMDs) in treating atopic dermatitis (AD). The study authors designed the system to generate timely, high-quality evidence using sequential propensity sco
- Age-related Fibroblast Changes Drive Melanoma in Males, Study Sayshttps://practicaldermatology.com/news/age-related-fibroblast-changes-drive-melanoma-males-study-says/2468115/Age-related changes in fibroblasts contribute to development of aggressive, treatment-resistant melanoma in males, according to a Johns Hopkins Kimmel Cancer Center study published in Cell. The authors of the study, Dr. Ashani Weeraratna and colleagues, had previously shown in studies that
- Study Aims to Define Photosensitivity Diagnosis in Atopic Dermatitishttps://practicaldermatology.com/news/study-aims-define-photosensitivity-diagnosis-atopic-dermatitis/2467967/A new study aims to refine diagnostic criteria for photosensitivity in patients with atopic dermatitis (AD). “Previous reports have characterized photosensitivity in AD, but with differences in terminology and criteria,” the authors noted, suggesting a need for better guidance. The
- Review: No Safety Concerns for Live Vaccines with Dupilumabhttps://practicaldermatology.com/news/systematic-review-no-safety-concerns-live-vaccines-dupilumab/2467944/Live vaccines are likely safe and effective for patients undergoing dupilumab treatment, according to results from a systematic review and expert consensus. Authors for a new systematic review, combined with expert input from a Delphi panel, provided insights into the safety and efficacy o
- New Plasma Proteins Linked to Atopic Dermatitis Riskhttps://practicaldermatology.com/news/new-plasma-proteins-linked-atopic-dermatitis-risk/2467771/New research has identified eight plasma proteins associated with atopic dermatitis (AD), potentially opening new avenues for treatment. Publishing in the Archives of Dermatological Research, the study authors used summary-data-based Mendelian Randomization (SMR) and evaluated dat
- Weekly Cendakimab Dosing Effective in Reducing AD Severityhttps://practicaldermatology.com/news/weekly-cendakimab-dosing-effective-reducing-ad-severity/2467489/New research shows that cendakimab is safe and efficacious at certain dosing levels over a 16-week study period in patients with moderate-to-severe atopic dermatitis (AD). The study authors for the phase 2 trial included 221 adult patients with moderate-to-severe AD from the United States