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- Phase 1 Data: Kymera Therapeutics’ IRAK4 Degrader Shows Promise in AD, HShttps://practicaldermatology.com/news/phase-1-data-kymera-therapeutics-irak4-degrader-shows-promise-in-ad-hs/2462133/Kymera Therapeutics, Inc. KT-474 (SAR444656), a potent, highly selective, orally bioavailable IRAK4 degrader, is showing early promise in Hidradenitis Suppurativa (HS) and Atopic Dermatitis (AD), according to a Phase 1 Trial published online in Nature Medicine. There was a reduction of disease-rel…
- Ankyra Therapeutics and Regeneron to Evaluate ANK-101 in Combination with Cemiplimab in Patients CSCChttps://practicaldermatology.com/news/ankyra-therapeutics-and-regeneron-to-evaluate-ank-101-in-combination-with-cemiplimab-in-patients-cscc/2462132/Ankyra Therapeutics will be working with Regeneron to evaluate ANK-101 in combination with Regeneron’s anti-PD-1 therapy, Libtayo (cemiplimab) in patients with cutaneous squamous cell carcinoma (CSCC) via a new a clinical trial supply agreement. ANK-101 is a novel first-in-class anchored IL-12 imm…
- FDA Accepts sBLA for Interchangeability Designation for Hadlima, a Humira Biosimilarhttps://practicaldermatology.com/news/fda-accepts-sbla-for-interchangeability-designation-for-hadlima-a-biosimilar-to-humira/2462131/The U.S. Food and Drug Administration (FDA) has accepted the Supplemental Biologics License Application (sBLA) for the interchangeability designation or Hadlima (adalimumab-bwwd) injection 40 mg/0.4 mL, a biosimilar to Humira(adalimumab). Once a biosimilar product is designated as an interchangeab…
- Language Barriers Linked to Underdiagnosis of Eczema and Other Allergic Conditionshttps://practicaldermatology.com/news/language-barriers-linked-to-underdiagnosis-of-eczema-and-other-allergic-conditions/2462128/Language barriers may cause some kids with allergic conditions such as eczema, food allergy, and asthma to be underdiagnoses, according to research presented at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Anaheim, CA. “We wondered if those who spoke …
- Is Lower Extremity Lymphedema a Risk for Skin Cancer?https://practicaldermatology.com/news/is-lower-extremity-lymphedema-a-risk-for-skin-cancer/2462127/Patients with lymphedema may have twice the risk of developing basal cell carcinomas and squamous cell carcinomas on the lower extremities than their counterparts without lymphedema, according to a retrospective study published in the November 2023 issue of the Mayo Clinic Proceedings. The study …
- CeraVe Launches in Indiahttps://practicaldermatology.com/news/cerave-launches-in-india/2462126/L'Oréal Dermatological Beauty recently unveiled CeraVe in India. To support the launch, the brand hosted 'Skin Barrier Science - A Dermatological Summit' in Mumbai, with dermatologists, experts, and partners from all over India and the world to highlight the importance of providing patients with a…
- Revance's Erica Jordan Promoted to CCOhttps://practicaldermatology.com/news/revances-erica-jordan-promoted-to-coo/2462124/Erica Jordan is now Revance Therapeutics, Inc.’s Chief Commercial Officer (CCO), Aesthetics. “Given the importance of the DAXXIFY launch, I’m excited to elevate Erica to the position of Chief Commercial Officer, Aesthetics reporting directly to me. Having worked closely with Erica over the past s…
- Updated AAD Guidelines on AD in Adults Back Use of Biologics, JAK Inhibitorshttps://practicaldermatology.com/news/updated-aad-guidelines-on-ad-in-adults-back-use-of-biologics-jak-inhibitors/2462123/Updated American Academy of Dermatology (AAD) guidelines on systemic treatment of atopic dermatitis (AD) in adults strongly back the use of dupilumab, tralokinumab, abrocitinib, baricitinib, and upadacitinib. “When the last guidelines were published in 2014, only non-targeted, off-label systemic m…
- TNF Blockers Are Not Associated With Poor Pregnancy Outcomeshttps://practicaldermatology.com/news/tnf-blockers-are-not-associated-with-poor-pregnancy-outcomes/2462122/Continuing tumor necrosis factor (TNF) inhibitors during pregnancy is not associated with worse fetal or obstetric outcomes and may reduce the risk of severe maternal infections during pregnancy, according to research presented at ACR Convergence 2023, the American College of Rheumatology’s (ACR) …
- ACR Update: TAK-279 Shows Promise in Phase 2b Psoriatic Arthritis Studyhttps://practicaldermatology.com/news/acr-update-tak-279-shows-promise-in-phase-2b-psoriatic-arthritis-study/2462119/Takeda's investigational tyrosine kinase 2 (TYK2) inhibitor TAK-279 showed significant efficacy in patients with active psoriatic arthritis, according to Phase 2b data slated to be presented at the American College of Rheumatology's (ACR) annual meeting in San Diego, California. TAK-279 is a highl…