Showing 3031-3040 of 3844 results for "".
- IEC Establishes Global Definitions for AD Disease Control and Remissionhttps://practicaldermatology.com/news/iec-establishes-global-definitions-for-ad-disease-control-and-remission/2486652/A new consensus statement from the International Eczema Council (IEC) proposes standardized definitions for low disease activity (LDA), very low disease activity (vLDA), and remission in atopic dermatitis (AD), addressing what authors noted as a longstanding gap in
- GPX4 Modulator Shows Early Promise in First-in-Human Studyhttps://practicaldermatology.com/news/gpx4-modulator-shows-early-promise-in-first-in-human-study/2486474/A novel topical therapy targeting cellular senescence showed early biologic activity across multiple dermatologic conditions in a Phase 1 clinical trial, according to data presented by Frederick Beddingfield III, MD, PhD, FAAD, at the Dermatology Innovation Forum during the American Academy of De
- IL-15 Blockade Plus Phototherapy Shows Promise in Vitiligohttps://practicaldermatology.com/news/il-15-blockade-plus-phototherapy-shows-promise-in-vitiligo/2486454/Targeting IL-15 with ordesekimab in combination with narrowband ultraviolet B (nbUVB) phototherapy led to greater repigmentation in patients with non-segmental vitiligo, according to results from a randomized, placebo-controlled trial presented by Brett King, MD, PhD, at the American Academy of D
- Amlitelimab Shows Efficacy Across Phase 3 AD Trialshttps://practicaldermatology.com/news/amlitelimab-shows-efficacy-across-phase-3-ad-trials/2486422/Late-breaking Phase 3 data presented at the American Academy of Dermatology (AAD) 2026 Annual Meeting demonstrated that amlitelimab, a nondepleting anti–OX40 ligand (OX40L) antibody, significantly improved disease severity and symptoms in patients with moderate-to-severe atopic dermatitis (AD), b
- Study Links MRGPRX3 Expression to Chronic Pruritus in PN and ADhttps://practicaldermatology.com/news/study-links-mrgprx3-expression-to-chronic-pruritus-in-pn-and-ad/2486413/In a prospective analysis of skin biopsies, investigators reported significantly elevated cutaneous MRGPRX3 expression in lesional prurigo nodularis (PN) and atopic dermatitis (AD), alongside a notable association between MRGPRX3-related gene mutations and Black pa
- Air Pollution Linked to Increased Psoriasis Burden: Meta-Analysishttps://practicaldermatology.com/news/air-pollution-linked-to-increased-psoriasis-burden-meta-analysis/2486409/New research presented at AAD 2026 suggests airborne pollutant particulate matter less than 2.5 microns in diameter (PM2.5), PM10, and NO2 showed the most consistent positive associations with psoriasis incidence in severity, and health care utilization.
- FDA Expands Secukinumab to Adolescents With Moderate to Severe HShttps://practicaldermatology.com/news/fda-expands-secukinumab-to-adolescents-with-moderate-to-severe-hs/2486084/The US Food and Drug Administrationv (FDA) has approved secukinumab (Cosentyx, Novartis) for pediatric patients aged 12 years and older with moderate to severe hidradenitis suppurativa (HS), becoming the only IL-17A inhibitor approved for this group, according to a
- ORKA-001 Phase 1 Data Support Potential Once-Yearly IL-23 Dosinghttps://practicaldermatology.com/news/orka-001-phase-1-data-support-potential-once-yearly-il-23-dosing/2485550/A half-life–extended IL-23p19 monoclonal antibody demonstrated sustained pharmacokinetics and favorable tolerability that may support once-yearly dosing in plaque psoriasis, according to “Phase 1 Clinical Data of ORKA-001, a Novel Half-Life–Extended IL-23p19 Monoclonal Antibody,” a poster by Jame
- Rezpegaldesleukin Demonstrates Broad Phase 2b Efficacy in Atopic Dermatitis and Asthmahttps://practicaldermatology.com/news/rezpegaldesleukin-demonstrates-broad-phase-2b-efficacy-in-atopic-dermatitis-and-asthma/2485541/Rezpegaldesleukin significantly improved disease severity, itch, and asthma-related symptoms in patients with moderate-to-severe atopic dermatitis, according to “Rezpegaldesleukin, Novel Treg-Inducing Therapy, Demonstrates Efficacy in Atopic Dermatitis and Asthma in a Phase 2b Trial,” a poster by
- Dr. Sheila Fallon Friedlander Highlights Pediatric Prevention, Guidelines, and Practical Care at Maui Derm Hawaiihttps://practicaldermatology.com/news/dr-sheila-fallon-friedlander-highlights-pediatric-prevention-guidelines-and-practical-care-at-maui-derm-hawaii/2485512/Giving clinicians tools they can use “in the here and now” was the theme as Sheila Fallon Friedlander, MD, presented on pediatric dermatology in one of the opening talks at Maui Derm Hawaii 2026. Dr. Friedlander covered prevention strategies, recent guideline updates, treatment safety (esp