New Masks and Botanical Facial Oil, Aforé by Dr. Few

Aforé by Dr. Few, a clinically developed skincare range founded on Dr. Julius Few’s innovative Four Dimensional Beauty approach, introduced three new products to the healthy aging skincare line.

Aforé Lactic Acid Pumpkin Mask exfoliates the skin to improve the appearance of fine lines, age spots, freckles, and rough skin. It minimizes pore size and other skin imperfections while stimulating the production of new, healthy cells with a combination of aloe vera, pumpkin enzymes, and pumpkin pulp extract.

Aforé Collagen Mask is a nourishing treatment for normal to dry skin. Nutrient rich native collagen, vitamins, and natural oils help to increase the skin’s moisture level to prevent early appearance of wrinkles and help the skin breathe easily during the cell renewal process.

Aforé Hydrating Facial Oil has jojoba seed oil, sunflower oil, argan oil, and rose hip oil blend with green tea and essential oils of yiang yiang, bergamot, and cedarwood to delight the senses and energize skin. This botanical antioxidant facial oil helps reduce the appearance of fatigue for skin that looks fresh and healthy all day. aforebeauty.com

New Mega Size 8-in-1 BioSerum, DefenAge

DefenAge Skincare added a new larger option of its 8-in-1 BioSerum to its line. DefenAge added 0.5 ounces to the standard size of its iconic bestseller and concept anti-aging cream. The 8-in-1 BioSerum is formulated to rejuvenate the skin’s smoothness, radiance, and hydration while minimizing the appearance of lines, wrinkles, age spots, redness, and pore size, and visibly brightening skin. The core of the product’s technology is DefenAge’s proprietary Age-Repair Defensins that are infused in the product at the highest daily concentration and backed by seven clinical studies, according to the company. defenage.com

LED Light for Loupes and Face Shields, Enova Illumination

Enova Illumination introduced the new Axis LED Light with Activ Battery System, the first LED light solution to pair a clip-on magnetic light with a wearable neckband battery for improved comfort and visualization during cosmetic facial procedures. The Axis clip-on magnetic LED light offers 30,000 lux illuminance for more than five hours of working time. The Axis light delivers bright, uniform illuminance filling the entire viewing field without shadowing or glare. When used with 2.5x magnification at a working distance of 14 inches, the Axis light illuminates a uniform four-inch spot field. Made of lightweight, aircraft-grade aluminum, the LED light is built for durability, withstanding frequent cleaning and disinfecting procedures. The Activ battery integrates Enova’s long-life battery technology into a comfortable, wearable design that rests around the neck, eliminating head weight and strain, the company says. This neckband battery is equipped with touch technology that allows the user to easily control three brightness settings. This solution is ideal for current PPE recommendations, according to the company. Practitioners can adjust the light underneath a disposable gown and without removing disposable gloves. A lightweight capacitive touch button activates the light and adjusts the brightness. The magnetic attachment is designed to be affixed on most face shields and can be directly mounted to most loupes. Attaching the magnet coaxially, down between the eyes, on face shields minimizes shadows and allows for better viewing of the procedure area. Goenova.com

NuPeel Natural Enzyme Peel, Theraderm

Theraderm’s NuPeel Natural Enzyme Peel is now available to help hydrate dry skin. The product is designed to gently remove dead skin cells to promote glowing, radiant skin appearance. Formulated with papaya enzymes to naturally exfoliate the skin, and botanical extracts like aloe, pineapple, grape seed, green tea leaf and cucumber to soothe it, NuPeel will help smooth out complexion and brighten skin. NuPeel is non-abrasive, non-irritating, and will help patients achieve that coveted post-peel glow—with none of the pain or peeling/drying side effects. The company said it also works on elbows, feet, knees, and other notoriously dry areas to soften skin. Theraderm.net

JLo Beauty Skincare Collection, Jennifer Lopez

Jennifer Lopez introduced JLo Beauty, a luxurious skincare collection infused with her expertise and experience and developed by Ascendant Beauty LLC, a joint venture between Guthy-Renker and BRX GR LLC. For her hero ingredient, Ms. Lopez was inspired by an old family secret—olive oil—but challenged her formulators to create something new, innovative, and groundbreaking. Enter the proprietary JLo Beauty Olive Complex: a four-part olive blend of squalane, fermented oil, extra virgin oil, and leaf extract that delivers antioxidant protection, and is clinically shown to deliver all-day moisturization and that “star glow.” The eight-piece collection reflects two years of product development and over 100 reformulations and includes:

• That Hit Single In A Gel Cream Cleanser
• That Jlo Glow In A Multitasking Serum
• That Limitless Glow In A Multitasking Mask
• That Blockbuster In A Nonstop Wonder Cream
• That Big Screen In A Broad Spectrum Spf 30 Moisturizer
• That Fresh Take In A Fierce Eye Cream
• That Star Filter In An Instant Complexion Booster
• That Inner Love In A Skin-Nutritious Dietary Supplement

The line launched on January 1, 2021. jlobeauty.com

New in My Practice: Devices

In each issue, Practical Dermatology® magazine spotlights a new device or over-the-counter or prescription medication dermatologists are recommending to patients. Deanne Mraz Robinson, MD, President and Co-Founder of Modern Dermatology in Westport, CT and an Assistant Clinical Professor of Dermatology at Yale New Haven Hospital, gives us a sneak peek at Endo Aesthetics’ Qwo for cellulite, which is slated to launch in Spring 2021.

What is Qwo, and how will you use it in practice?

Deanne Mraz Robinson, MD: Qwo is the first FDA-approved injectable for the treatment of cellulite in adult women. Qwo is an injectable collagenase clostridium histolyticum-aaes (CCH-aaes), which specifically targets Type 1 and Type 3 collagen. I am an investigator for a Phase 3B “Real World” study treating buttocks and thighs which is still ongoing.

How does Qwo compare to other cellulite reduction techniques and technologies?

Dr. Robinson: There are FDA-cleared devices that also get to the root cause of cellulite, those fiborous bands under the skin, but Qwo is an injectable and patients are very familiar with aesthetic injectables. There are a lot of injectables for facial aesthetics. There are devices focused on body contouring. But if you think about it, Qwo is really the convergence of both those markets. What is exciting about Qwo is that after it is injected, enzymatic subcision and remodeling (ESR) begins. ESR is believed to initiate as the enzymes work on the fibrous septae to release the cellulite dimple. This enzymatic activity stimulates neocollagenesis. From within, this collagen support network rebuilds itself in the extracellular matrix with thinner, smaller septae. These subdermal changes reduce tension and help thicken the dermis, creating a smoother appearance.

Can you offer any Qwo treatment pearls/protocols?

Dr. Robinson: Treatment visits for Qwo should be repeated every 21 days for three treatment visits. There is some localized bruising post treatment, so patients should plan their visits accordingly. During clinical trials, Endo took “after” pictures 71 days following the first injection. Patients returned for their final “after” photo 28 days after their third treatment. The long-term durability data from the Phase 2 study was presented at the American Society for Dermatologic Surgery annual meeting. The conclusion of this publication was that CCH-aaes provided durable improvement in cellulite appearance up to four years after initial dosing and was generally well tolerated.

Who is an ideal patient for Qwo?

Dr. Robinson: Qwo is approved for use on the buttocks of adult women. Any woman who is bothered by the dimples, not waves, on their buttocks could be a good candidate for Qwo. Side effects of Qwo included injection site bruising, pain, areas of hardness and itching in the treatment area.

How has patient satisfaction been with Qwo?

Dr. Robinson: The trials conducted to evaluate Qwo for the treatment of cellulite in adult women remain the largest cellulite studies ever conducted, with 845 participants. At day 71, physicians and patients were asked, independently, to assess the appearance of cellulite in each buttock on a photo-numeric cellulite severity scale (PCSS). Endo studied all Fitzpatrick skin types with nearly 30 percent of those treated with Qwo being Fitzpatrick IV, V, and VI. The primary endpoint was the percentage of subjects who had a 2-level improvement on both the patient- and physician-reported scales of cellulite severity. A greater percentage of the 843 women treated during the studies met the primary endpoint. In addition, statistically significant improvements with Qwo versus placebo were observed for 8 of 8 (in RELEASE 1) and 7 of 8 (in RELEASE 2) secondary endpoints in target buttocks including the percentage of subjects who experience at least a 1-level or 2-level improvement in patient-reported assessment, the percentage of subjects with a 1-level composite improvement, the percentage of subjects with at least a 1-level or 2-level improvement in the global aesthetic improvement scale (GAIS), percentage of subjects with a 2-level composite improvement in non-target buttocks, percentage of satisfied subjects and change from baseline in a cellulite impact scale (i.e., patients’ self-perception related to their cellulite).

How do you combine it with other treatments for maximum results?

Dr. Robinson: As it is not commercially available and has only been used in the research setting, I have not combined it with other treatments. I can imagine combining it with non-invasive fat reducing modalities and or biostimulatory fillers.