New Products

Dermal Repair Ultra-Nourish, Senté

Senté’s new Dermal Repair Ultra-Nourish is uniquely formulated for drier, sensitive skin types. This lipid replenishing cream combines Heparan Sulfate Analog (HSA) and a unique blend of lipids to nourish and smooth skin while improving the appearance of fine lines and wrinkles, redness, and skin tone and texture. Senté’s, patented HSA targets the underlying causes of inflammation and supports the skin’s natural ability to repair itself. HSA is clinically shown to deliver deep hydration, decrease visible redness, and improve the appearance of fine lines and wrinkles. Dermal Repair Ultra-Nourish is non-comedogenic, hypoallergenic, and dermatologist-tested. Sentelabs.com

Age Reverse+ Rebuild-5 Cream, Exuviance

Exuviance has introduced Age Reverse+ Rebuild-5 Cream. It’s formulated with five rejuvenating ingredients: MicroDiPeptide229, Peony Botanical, Aminofil, PHA, Vitamin E. MicroDiPeptide229 is a dermatologist-developed peptide that was created for optimal delivery into the skin’s surface. This scientifically proven molecule supports all five of skin’s natural building blocks including elastin, collagen, and hyaluronic acid to resist future signs of aging for naturally youthful looking skin. The company reports that after 12 weeks of twice-daily use, 94 percent of products users reported their cheekbones are more defined, 100 percent said skin appears lifted and fine lines are less visible, and 88 percent reported the jawline has a more contoured appearance. Exuviance.com

Neck Correct Cream, SkinMedica

SkinMedica Neck Correct Cream for Neck and Décolleté is formulated to target and treat areas of concern to visibly hydrate, lift, firm, and smooth the skin on the neck and counteract the appearance of horizontal lines, wrinkles, crepey-like skin and sagging on the neck. It combines SkinMedica’s signature antioxidant blend with power-house peptides, Green Microalgae, Lemon Balm, and Shitake Mushroom extracts. In clinical studies, improvements were found in the visible signs of neck aging. At Week 12 for the neck, 98 percent of users reported it made their skin feel smoother, 88 percent reported it improved the texture of their skin, 86 percent reported it improved the overall health and look of their neck. At Week 12, on the décolleté, 98 percent reported it made their skin feel smooth and soft, 91 percent reported it improved the texture of their skin. Skinmedica.com

NEW DERMA+ Antiperspirant, Secret

Secret’s NEW DERMA+ Antiperspirant with DERMA-Shield Formula revitalizes underarm skin to help fight the five signs of shave irritation (dryness, redness, bumps, nicks and discoloration), while providing odor and sweat protection. Developed by a team of female dermatologists and accredited by the Skin Health Alliance, DERMA+ is the culmination of 10 years of research and development. DERMA+ is designed Secret’s first-ever squeezable tube packaging and soft touch applicator. Now users can dispense and apply at their own command. DERMA+ is available in four varieties including: Nourishing Coconut Oil, Cooling Aloe, Fragrance Free, and Even Tone Vitamin C. Secret.com

New in My Practice: Zerigo Health Solution

With Jashin J. Wu, MD

In each issue, Practical Dermatology® magazine spotlights a device or over-the-counter or prescription medication that dermatologists are recommending to patients. Here, Jashin J. Wu, MD, founder and CEO of the Dermatology Research and Education Foundation and Founder and Course Director of four dermatology symposia in Irvine, CA, discusses how the Zerigo Health Solution is changing the way that psoriasis patients who need phototherapy are being treated.

What is the Zerigo Health Solution?

Jashin J. Wu, MD: Zerigo Health’s connected home phototherapy treatment platform (Zerigo Health Solution) is cleared for psoriasis. The handheld Narrowband UVB (NB-UVB) phototherapy treatment device plus the patient’s mobile phone help manage dosing, treatment frequency, and duration of therapy, according to the prescription. All the treatment, adherence, and patient-reported outcomes data are then aggregated and analyzed in Zerigo’s cloud-based software application and condensed into summary progress reports to monitor patient progress, counsel patients during follow-up visits, and monitor for side effects. Zerigo has a group called CarePartners who are trained phototherapy experts and care coordinators. They also use this real-time treatment data to monitor all patients on therapy and provide them with personal coaching and support to help them throughout their treatment journey.

Which patients benefit most from the device?

Dr. Wu: I recommend Zerigo for mild to moderate psoriasis more than other conditions. The ideal patients present with three percent to 10 percent affected body surface area. Patients who are tech-savvy tend to prefer this type of self-delivered care, but all patients can benefit from using this treatment model. Patients who prefer to have their phototherapy at home, live far from the clinic, or have a busy work or school schedule benefit from it. During the COVID-19 pandemic, this has been my recommended method of phototherapy. Patients also appreciate not having to come to the clinic for follow-up visits. It is available for Medicare & Tricare beneficiaries (for the treatment of psoriasis) and members of health plans and self-insured employers which cover the Zerigo Health Solution as part of their health benefits program. Unfortunately, it’s not available for out-of-pocket purchase.

How do you suggest they use the device?

Dr. Wu: Usually, patients need therapy three times a week for the first eight to 12 weeks, which is called the induction phase. Once they are clear or nearly clear, they can reduce to once per week or once every two weeks to maintain their response. Many times, patients will want to take a break completely during the summer months, but then in the winter when they flare, they will return to the home phototherapy. One of the unique attributes of the Zerigo Health Solution is that it manages the patient’s treatment schedule, including dosing, frequency, and duration, per the protocol that is prescribed. On a treatment day, the patient gets a treatment reminder through the Zerigo app at the time that they designate as most convenient for them and simply turn on the device and press one button to begin treating with protocol-driven dosing automatically calculated via the app. From a physician control and patient convenience standpoint, this connected system is superior to the legacy home phototherapy devices that have been used historically.

Is the Zerigo Health Solution device used with other therapies?

Dr. Wu: I tend to use it as monotherapy for mild to moderate psoriasis, but it certainly can be used in combination with topical therapy, oral therapy, or biologics.

What type of results are your patients seeing?

Dr. Wu: Zerigo conducted a small prospective, interventional study which demonstrated comparable outcomes to outpatient NB-UVB therapy. At 10 weeks, all patients experienced improvement in the treated lesions, with a mean improvement in Psoriasis Severity Index of 57 percent. Because Zerigo can monitor adherence and outcomes remotely via its software application, we see patients progressing and clearing. This data is available to prescribing clinicians in succinct progress reports which can be used to counsel patients during follow-up visits. Zerigo has also measured consistently high levels of patient treatment satisfaction at more than 80 percent.

Is there any learning curve to its use?

Dr. Wu: As with all devices, there is a learning curve, but I think most patients can learn it quickly. The smartphone app is intuitive to use and very convenient for the patient. We are seeing that compliance increases because the patient can schedule their treatments when convenient for them, are reminded to treat via the app, and monitored and supported by Zerigo care coaches. The patient also takes a more active role in this therapy model and can track their own improvement over time, which is empowering.

How does the Zerigo Health Solution compare to other UV light home devices?

Dr. Wu: Compared to legacy home UVB devices, there is less paperwork to review with patients, which results in a quicker visit and a lower risk of burns. Several recent studies show that adherence using the Zerigo Platform is greater than 90 percent. Compared to published phototherapy adherence rates of legacy phototherapy devices, there is a 20-25 percent or more absolute adherence rate improvement seen with the Zerigo Platform. It also is the only device which uses and is linked to a patient’s mobile app.