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Isdin’s Melaclear Advanced

With Claire Wolinsky, MD

In each issue, Practical Dermatology® magazine taps top dermatologists to ask about the newest cosmeceuticals they are offering to patients. Here, Claire Wolinsky, MD, a dermatologist in New York City, shares how Isdin’s latest launch, Melaclear Advanced, is giving pigment a run for its money.

What is Isdin’s Melaclear Advanced?

Claire Wolinsky, MD: Isdin’s Melaclear Advanced is a pigment-correcting gel-like serum with a nice fragrance. Actives include tranexamic acid, niacinamide, and Spot Corrector Complex, a patented blend of exfoliating acids and a tyrosinase inhibitor, and licorice root. The tranexamic acid and Spot Corrector Complex work together to brighten and correct while the niacinamide and licorice root soothe and hydrate skin. Together, these ingredients can address stubborn pigmentation across all skin types.

How does Isdin’s Melaclear Advanced stand out from other pigment correctors?

Dr. Wolinsky: Pigment is a huge market. There is a long list of patients coming in with sunspots, melasma, and post-inflammatory hyperpigmentation. Hydroquinone is still the gold standard for hyperpigmentation, but some dermatologists steer away from it due to risks. After a couple of months of hydroquinone use, pigmentation comes back.

Melaclear Advanced hits the induction stage of melanin production. It provides great results, and there is no risk of rebound pigmentation. The tyrosinase inhibitor blocks tyrosinase, which is responsible for the first step in melanin production. The packaging is recyclable and refillable. All Isdin products are sustainable at a corporate level.

How do you tell patients to use Isdin’s Melaclear Advanced?

Dr. Wolinsky: I tell my patients to use it twice a day, but if their skin gets dry, they can use it once a day and will still see benefits.

What kind of benefits are patients seeing with Isdin’s Melaclear Advanced?

Dr. Wolinsky: My patients are seeing visible improvements as early as 2 weeks and dramatic results by 12 weeks including improved radiance, skin tone, and texture, plus a reduction of dark spots, discoloration, hyperpigmentation, and photodamage.

What procedures does Isdin’s Melaclear Advanced complement?

Dr. Wolinsky: Melaclear Advanced is an ideal at-home complement to chemical peels and non-ablative laser skin rejuvenation. I suggest patients layer it on top of vitamin C serum with a retinoid but carefully as there could be a cumulative irritation. A broad-spectrum, high-SPF sunscreen like Eryfotona Actinica or Ageless should be applied last.


UV Luminous Broad-Spectrum SPF 41, EltaMD

EltaMD recently introduced a new lightweight, all-mineral, broad-spectrum tinted sunscreen with a semi-matte appearance. The non-comedogenic formula has a mousse-like consistency that will not clog pores or cause breakouts, according to the company. The antioxidant blend reduces free radicals to help diminish the visible signs of aging associated with UV, HEV, and IR. It’s an ideal choice for post-procedure sun protection by helping to blur imperfections. The sunscreen absorbs quickly, can be used alone or under makeup for a semi-matte finish, and is free of dyes, fragrance, oil, and parabens. EltaMD.com

Body Care Products for Tone/Texture and Eczema-Prone Skin, Aveeno

Aveeno’s new Tone + Texture Daily Renewing Lotion and Tone + Texture Overnight Renewing Cream were created to address individual skin concerns such as bumpy skin (including keratosis pilaris), roughness, and discoloration and to visibly improve tone + texture.

The latest addition to the Aveeno Eczema Therapy Line, the Aveeno Eczema Therapy Rescue Relief Treatment Gel Cream (1.5 fl. oz. & 5 fl. oz. option), is clinically proven to soothe itch, dryness, and irritation due to eczema and works to tackle eczema flare-ups quickly and on-the-go. Aveeno.com

pHisoderm Clean, pHisoderm

Since the start of the COVID-19 pandemic, consumers are more in tune with their skin health and are going out of their way to purchase clean products designed for their skin. Introducing pHisoderm Clean, a line of clean, dermatologist-recommended cleansers that are pH-balanced and uniquely designed for specific skin types; sensitive, dry/combination, and acne-prone skin. pHisoderm Clean products are mindfully crafted without any parabens, soap, alcohol, dyes, mineral oil, and sulfates, all ingredients that can harm or irritate your skin. The skin-type specific formulas cleanse and provide unique benefits to improve skin health. The Anti-Blemish Facial Cleanser and Body Wash treat blemishes with 2% salicylic acid, while the hyaluronic acid locks in moisture even after rinse off. Not only does the Sensitive Skin Cream Cleanser calm skin with sunflower seed oil, vitamin E, and aloe vera, it’s specifically formulated without any fragrances, which can be irritating to sensitive skin. While working hard to clean skin of dirt, oil, and makeup, the Moisturizing Cream Cleanser packs a hydration punch with a unique combination of sunflower seed oil, vitamin E, chamomile, aloe vera and an oat-inspired skin conditioner. Each formula is uniquely designed with a balanced pH level that brings skin back to balance; lower pH levels for blemish-prone skin to help acne from forming and create the optimal environment for the salicylic acid to get to work. The mid-range pH levels in the Sensitive Skin Cream Cleanser and Moisturizing Cream Cleanser help revitalize dry, combination, and sensitive skin. phisoderm.com 

Skincare Line, OXY

For almost 50 years, OXY Skin Care has been a trusted brand that has helped build the confidence of those with acne-prone skin. Today, OXY Skin Care’s entire line of effective acne treatments is now dermatologist-recommended and delivers gentle and soothing skincare. Formulated to be strong and effective yet gentle on skin, OXY Skin Care products promise clear, healthy skin at affordable price points. The OXY Advanced Care with Prebiotics line is uniquely formulated with plant-based prebiotics that rebalance the skin’s microbiome and promote healthy skin. OXY Advanced Care Rapid Spot Treatment with Prebiotics is clinically proven to work up to six times faster and is designed for all skin tones. OXY Cleansing Acne Pads contain clinically proven salicylic acid to unclog pores, exfoliate skin, and treat and help prevent acne to allow skin to heal. Designed with an effective combination of hyaluronic acid plus dermatologist-recommended acne medications, OXY Total Care eliminates acne and smooths and hydrates all skin types at any age. OXYSkincare.com

R+F Haircare Collection, Rodan + Fields

Developed with Rodan + Fields’ 30+ years of expertise and a deep understanding of dermatology-based skincare, the R+F Haircare Collection takes a scalp-first approach to deliver deeply transformative, clinically tested results instantly and over time. The introduction to the hair category represents a significant opportunity for Rodan + Fields and its independent consultants to empower entrepreneurs and provide visible results to customers. Healthy hair needs a healthy scalp and care that goes beyond the surface. Each thoughtfully blended formula contains high-quality, clinically tested skincare and hair care ingredients blended in just the right way and applied in exactly the right order to nourish roots, repair damage, protect color and help support long-term healthy hair. Featuring Rodan + Fields proprietary RF TriEnergy Complex, the products are designed to energize, strengthen, and protect hair, while skincare ingredients like amino acids and silk peptides protect color, repair damage, and nourish roots. R+F Haircare is launching with eight products, including two Regimens, Smooth+ and Volume+ and two styling treatments. rodanandfields.com

Men’s Skin Provision System, DefenAge Skincare

DefenAge Skincare has launched its first skincare system developed specifically for men. Evolved from the DefenAge Men’s Skincare Kit, the brand’s highly successful and popular skincare set for men, the new Men’s Skin Provision is further tailored directly to men’s unique needs and expectations for skincare products. The Men’s Skin Provision set is centered around the regenerative power of DefenAge’s proprietary Defensin-molecules, which naturally refresh and renew skin (US Patent No. 11,491,096). This scientifically proven technology is an effective solution for daily skin maintenance, as it promotes healthy skin that looks fresh, energized, and young. The simple-to-use two-step system contains a face cleanser and moisturizer. Through an innovative formulation, DefenAge discovered a way to make the new moisturizer, 24/7 Barrier Balance Cream - Men’s Formula, just as effective as DefenAge’s award-winning, clinically proven multi-step system, cutting down on time and steps and creating a more simple and efficient system for men. Formulated for men, the innovative moisturizer received an advanced inflammation-controlling system for smoothing and calming as well as an upgraded super-charged moisturization complex. It also contains barrier protection ingredients, antioxidants, vitamins, and vital nutrients for skin. Additionally, DefenAge developed a Men’s Skin Booster to jump-start the skin for high-performance use once or twice a year. This system contains a full-sized DefenAge 1-Step-Multi-Cleanse and 24/7 Barrier Balance Cream - Men’s Formula, plus a “booster” of the Defensins-packed 8-in-1 BioSerum and exfoliating 2-Minute Reveal Masque to optimize skin regeneration and cell turnover. Defenage.com

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