SkinCeuticals Advanced Corrective Peel

SkinCeuticals new exclusive professional peel was developed to provide comprehensive texture refinement and the improvement of discoloration and hyperpigmentation with minimal downtime. Customizable, comprehensive, and universal, the company says, the peel protocol utilizes layering to control and adapt application and penetration, and has been proven safe and effective on all skin types and Fitzpatrick levels. The peel targets enlarged pores, dullness, uneven tone and texture as well as hyperpigmentation with a blend of clinical-grade acids, including salicylic acid, lactic acid, and phenylethyl resorcinol. Clinical studies showed after a series of four treatments, more than a 20 percent improvement in pore appearance, sun and dark spots, and more than a 40 percent improvement in overall radiance and skin texture. Skinceuticals.com

NeoStrata Ultra Smoothing Lotion

NeoStrata launched a new lotion for patients with keratosis pilaris (KP). NeoStrata Ultra Smoothing Lotion is a light, translucent moisturizer that gently exfoliates skin and promotes cellular renewal to help rid pores of the abnormally accumulated keratin that causes bumps. With a combination of 8% Glycolic acid and 2% Citric acid, the lotion softens and smooths the face and body and works to relieve dry, rough, and damaged skin while reducing the appearance of fine lines and wrinkles. NeoStrata.com

Clarisonic Alpha Fit for Men

Clarisonic introduced the new Alpha Fit, its first device engineered specifically to clean men’s tougher skin. Using the company’s patented sonic technology, Alpha Fit was designed to cleanse away oil, sweat, and grime for healthier feeling, more energized. The device features two simple settings: (1) Clean-Shaven for daily cleansing to prep skin for a closer, smoother shave, and (2) Bearded or Power Cleaning—to deep clean for a more comfortable beard or for more cleansing power post-workout

After four weeks of use, 100 percent of men reported they felt their skin was cleaner, more comfortable, and smoother, and more than 90 percent of men experienced less shaving nicks, razor bumps, and a closer shave. After two weeks of use, more than 90 percent of men said they felt their skin was energized, revived and hydrated, and men with beards felt a cleaner, softer and more comfortable beard. Its compact, waterproof design fits in the palm of a user’s hand and is easily portable. The Alpha Fit kit includes a Men’s Daily Cleanse Brush Head and will be available beginning in September. Clarisonic.com

New Firm-NG6 Non-Acid Peel from Exuviance

Exuviance launched its new Firm-NG6 Non-Acid Peel. This one-step at-home peel is formulated with a powerful, yet gentle 6% concentration of NeoGlucosamine® to accelerate cell renewal while plumping the skin’s matrix to help firm and tighten skin and improve texture and tone. This peel includes an ingredient from the company’s patented portfolio that offers similar benefits as alpha hydroxy acids (AHAs) but in a non-acid form. Like AHAs, NeoGlucosamine® exfoliates skin, helps build the skin’s matrix to increase volume and reduces pigment to brighten skin. Exuviance.com

Therapeutics Focus: Acne

FDA Approves Epiduo Forte for Acne

The FDA approved Galderma’s antibiotic-free Epiduo® Forte (adapalene and benzoyl peroxide) Gel, 0.3%/2.5%, for the once-daily, topical treatment of acne vulgaris. Epiduo Forte Gel is the first combination of these strengths of the retinoid, adapalene, and benzoyl peroxide, developed for the treatment of patients in the moderate to severe acne population.

Read more in the news section on p. 11, or watch DermWireTV at DermWire.com.

Research Links Vitamin B-12
Supplement to Acne

New research by researchers at the David Geffen School of Medicine at UCLA found that vitamin B-12 tweaks how genes behave in the facial bacteria of some people with normal skin. The altered activity of the facial bacteria promotes inflammation and leads to pimples.

This UCLA research was initiated as part of the Human Microbiome Project. Launched by the National Institutes of Health in 2007, the project aims to identify and better understand the microorganisms living in and on our bodies that maintain human health and lead to disease.

The study authors note, vitamin B12 supplements have been shown to lead to acne development, but the mechanism behind this effect has remained unexplored. This new study shows that transcriptional changes in the skin microbiota contribute to vitamin B12–induced acne. Supplementing patients with vitamin B12 reduced the expression of vitamin B12 synthesis genes in Propionibacterium acnes and altered the transcriptome of the skin microbiota, resulting in the production of inflammation-inducing porphyrins, demonstrating a clear link between changes in the skin microbiome and disease pathology.

By shedding light on one mechanism behind B-12’s role in acne, the UCLA research may identify drug targets that lead to new treatments for acne.

The findings were published in the June 24 edition of Science Translational Medicine. n